Successful treatment of hypermagnesemia with atropine sulfate in sheep
نویسندگان
چکیده
A hypermagnesemic adult sheep during an experimental study showed gastraointestinal and respiratory changes along with cardiovascular alterations included of obvious bradycardia and heart block. In order to save the animal from fatal bradycardia, atropine sulfate was administrated instatntly at one dose 0.3 mg/kg. The animal was survived and rhythm returned to sinus rhythm from marked bradycardia and sinus arrest after administration of atropine. The present report describes signs of severe hypermagnesemia due to an overdose of magnesium sulfate during an experimental study and its successful therapeutic outcome.
منابع مشابه
مقایسه نتایج درمان با آتروپین سولفات و پیلورومیوتومی در شیرخواران مبتلا به استنوز هیپرتروفیک پیلور
Background & Aims: In hypertrophic pyloric stenosis (HPS) the hypertrophied muscles of pylorus cause partial gastric outlet obstruction. The standard management of HPS is pyloromyotomy. However, successful treatment of HPS with atropine sulfate also has been reported. We aim to compare the outcomes of medical and surgical treatment for HPS. Materials & Methods: In this comparative clinical tri...
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Atropine (AT) and oximes, alone or in combination, have been proven greatly valuable therapeutics in the treatment of organophosphates intoxications. An injectable mixture of AT and obidoxime (OB) was formulated for administration by automatic self-injector. The aqueous single dose solution contained 275 mg obidoxime chloride and 2.5 mg atropine sulfate per 1 ml (220 mg and 2 mg per 0.8 effecti...
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Development of a Combined Solution Formulation of Atropine Sulfate and Obidoxime Chloride for Autoinjector and Evaluation of Its Stability
Atropine (AT) and oximes, alone or in combination, have been proven greatly valuable therapeutics in the treatment of organophosphates intoxications. An injectable mixture of AT and obidoxime (OB) was formulated for administration by automatic self-injector. The aqueous single dose solution contained 275 mg obidoxime chloride and 2.5 mg atropine sulfate per 1 ml (220 mg and 2 mg per 0.8 effecti...
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